Abstract:Objective To investigate the infection rate and distribution of human papilloma virus (HPV) in women in Dongguan area, and to provide reference for clinical prevention and control measures. Methods Totally, 6,178 patients with HPV detection in gynecology clinic of Family Planning Service Center of Dongguan in Guangdong Province were selected as research objects. 1,232 patients under 30 years old were recruited into group A, 1,244 cases of 31-40 years old into group B, 1,238 cases of 41-50 years old into group C, 1,235 cases of 51-60 years old into group D and 1,229 cases of 61-70 years old into group E. The infection rate of HPV and the distribution of different virus types of HPV were statistically analyzed and compared among different groups. Results HPV was detected in 1,069 cases, with a positive rate of 17.30%. Among them, 771 cases (72.12%) were detected to have high risk HPV (HR-HPV), 142 cases (13.28%) to have low risk HPV (LR-HPV), and 156 cases to have uncertain type(14.59%). As for HR-HPV, HPV-16, HPV-52, HPV-58, HPV-18 and HPV-51 were common, accounting for 18.80%, 14.03%, 9.54%, 7.76% and 6.27% respectively in the positive samples. The detection rates of HPV and HR-HPV differed significantly among various groups(P<0.05), with the highest rates in group A (31.25% and 22.24%), and the lowest in group E (5.70% and 3.66%). The detection rates of LR-HPV, uncertain type and mixed infection were not statistically different among various groups(P>0.05). Conclusions The infection rate of HPV in women in Dongguan area is median, and HR-HPV is predominant. The women younger than 30 years with active sexual life have higher infection rate.
姜碧,钟鸣, 韦思似, 刘惠,姚倩瑜,叶泳, 卢海珍, 陈杞慧. 东莞地区6 178名妇女人乳头瘤病毒感染率及型别分布情况[J]. 实用预防医学, 2016, 23(7): 794-796.
JIANG Bi, ZHONG Ming, WEI Si-si, LIU Hui, YAO Qian-yu, YE Yong, LU Hai-zhen, CHEN Qi-hui. Infection rate and distribution of HPV in 6,178 women in Dongguan area. , 2016, 23(7): 794-796.