Abstract：Objective To investigate the epidemiological and clinical characteristics of influenza-associated hospitalization cases in Fangshan District, Beijing, and to provide evidence for their prevention and treatment. Methods A study was conducted among influenza-associated patients hospitalized in Liangxiang Hospital, Fangshan District, Beijing from April 2015 to April 2016. The patients’ nasopharyngeal swabs were sampled for laboratory testing; meanwhile, their related information, such as clinical characteristics, medical history and vaccination history was collected. Results A total of 1,093 influenza-associated hospitalized patients were enrolled in this study, and the positive detection rate of influenza viruses was 7.59%. Influenza B virus accounted for 61.45% of the detected viruses. The peak season of influenza epidemics was from the 2nd week to the 12th week in 2016. The incidence rates of cough (92.77% vs. 76.14%), expectoration (53.01% vs. 42.48%), bronchitis(28.75% vs. 13.17%), chronic obstructive pulmonary (9.64% vs. 1.39%), high fever and convulsion (5.00% vs.1.19%) were all significantly higher in the influenza viruse-positive cases than in the influenza viruse-negative ones (P<0.05), while the incidence rates of sore throat (15% vs. 25.74%) and acute tonsillitis (1.25% vs.14.06%) were both lower in the influenza viruse-positive cases than in the negative control cases. The median duration of hospital stay for the influenza-associated hospitalized patients was 6 days. The duration of hospital stay was closely related to the age group. The age groups of 10-<20 years (OR=0.066, 0.029-0.150, P=0.000), 20-<30 years (OR=0.314, 0.111-0.814, P=0.033) and 30-<40 years (OR=0.266, 0.077-0.917, P=0.035) played a protective role in the hospitalization time of the influenza-associated hospitalized cases. Conclusions Influenza B virus is the most predominant pathogen in the influenza-associated hospitalized patients in Fangshan District. Influenza viruses may aggravate respiratory tract infections. The age of 10-<40 years is a protective factor of the severity of the influenza-associated hospitalized cases.
石磊, 黄少平, 刘静, 田竞, 李丽丽, 张奕. 2015年4月-2016年4月北京市房山区流感相关住院病例的临床与病原学特征分析[J]. 实用预防医学, 2017, 24(9): 1051-1054.
SHI Lei, HUANG Shao-ping, LIU Jing, TIAN Jing, LI Li-li, ZHANG Yi. Clinical and etiological features of influenza-associated hospitalized cases in Fangshan District, Beijing, April 2015 to April 2016. , 2017, 24(9): 1051-1054.
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2017, Vol. 24 
