Abstract：Objective To investigate the epidemiological characteristics of metabolic syndrome (MS) in Nanjing residents, to explore its influencing factors, and to provide a scientific basis for the primary prevention and control strategy of MS and its related diseases. Methods With a multi-stage stratified cluster random sampling method, districts in Nanjing were divided into three layers according to the economic level. 2 districts were randomly selected from each layer, 6 community neighborhood committees from each district, and 75 households from each neighborhood committee. All the family members of the households selected served as the subjects for inquiry, dietary investigation, physical examination and laboratory test. General population aged ≥ 15 years served as the research subjects, factor analysis was performed to identify the dietary patterns, and multivariate unconditionallogistic regression analysis was used to identify the factors influencing MS. Results A total of 5,029 subjects were enrolled in this study. According to the diagnosis standard based on a joint interim statement issued by organizations such as the International Diabetes Federation, the crude prevalence rate of MS in the population aged ≥ 15 years was 30.98%, and the standardized prevalence rate 21.87%. The prevalence rate was higher in males than in females (24.31% vs.19.18%, χ2=19.420, P<0.001) as well as higher in urban areas than in rural areas (23.11% vs. 19.56%, χ2=8.115, P=0.004). The risk factors for MS included living in cities (OR=1.344, 95%CI:1.126-1.604), increasing age (OR65-year-old group=10.658, 95%CI:5.357-21.204), smoking (OR=1.222, 95%CI:1.008-1.480), long leisure sedentary time (OR=1.225, 95%CI:1.044-1.437), and increased BMI (ORobesity=18.491, 95%CI:14.887-22.969) and family history of hypertension (OR=1.164, 95%CI:1.010-1.342), while high education(ORcollege and above=0.693, 95%CI:0.515-0.932) was a protective factor. A total of 1,746 subjects were enrolled in dietary pattern analysis based on the food frequency data, and three dietary patterns, including pastry and beverage pattern, traditional vegetable pattern and western meat pattern, were extracted by factor analysis. In western meat pattern, subjects in the highest quartile had an increased risk of MS compared with those in the lowest quartile (OR=1.595, 95%CI:1.095-2.323, Ptrend=0.018). Conclusion The prevalence rate of MS in residents aged ≥15 years in Nanjing is high, which should be prevented and controlled by controlling body weight, changing smoking behavior, long leisure sitting time and unreasonable dietary structure and so on.
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