Abstract:Objective To explore the effect of health management mode on health behavior of women with high-risk papillomavirus (HPV) infection. Methods We selected 200 high-risk HPV-positive women as the research objects among the female permanent residents with cervical cancer screening in Shijie Town from January 2012 to December 2013. According to the principle of random grouping, the 200 women were divided into the experiment group and the control group (each n=100). The experiment group received health management interventions, regular follow-up and reexamination, while the control group only accepted regular follow-up and reexaminaiton. After implementing 1-year health intervention, the changes in the negative conversion rate of high-risk HPV infection, the virus load RLU/CO ratio and HPV-related knowledge, attitude and practice (KAP) were evaluated and compared between the two groups. Results After 1-year health intervention, the negative conversion rate of high-risk HPV infection was significantly higher in the experiment group than in the control group (32.0% vs. 15.0%), showing a statistically significant difference (χ2=12.47, P<0.05). The virus load RLU/CO ratio was significantly lower in the experiment group than in the control group, with a statistically significant difference (t=16.68, P<0.05). Before the intervention, no statistically significant difference was observed in the score of each dimension of HPV-related KAP between the two groups (all P>0.05). After the 1-year intervention, the score of each dimension of HPV-related KAP was significantly higher in the experimental group than in the control group, with statistically significant differences (all P<0.05). Conclusion Implementing health management among women with high-risk HPV infection can ameliorate their unhealthy behavior and further improve their HPV-related KAP so as to effectively increase the negative conversion rate of high-risk HPV infection, decline the virus load RLU/CO ratio, decrease the incidence of cervical cancer and improve their health level and quality of life.
薛珍,叶仕英,杜婉燕,胡桂贞,任里丽. 健康管理对感染高危型HPV妇女健康行为的影响[J]. 实用预防医学, 2017, 24(4): 446-448.
XUE Zhen, YE Shi-ying, DU Wan-yang, HU Gui-zhen, REN Li-li. Effect of health management on health behaviorof women with high-risk HPV infection. , 2017, 24(4): 446-448.