Abstract：Objective To analyze the changing trend of disease burden of stroke in Chongqing Municipality from 2012 to 2018, and to provide suggestions for stroke prevention and treatment. Methods Cases of stroke (ICD-10: I60-I64) in Chongqing Municipality from 2012 to 2018 were sorted from the National Registration and ReportingSystem forCardiovascular and Cerebrovascular Eventsdeveloped byChinese Center for Disease Control and Prevention. SPSS 25.0 software was used to statistically analyzed the incidence rate, age-standardized incidence rate (ASIR), mortality rate and age-standardized mortality rate (ASMR), disability adjusted life years (DALY), years of life lost (YLL), and years lived with disability (YLD). The trend change of the incidence rate, ASIR, mortality rate, ASMR, DALY, YLL and YLD of stroke were indicated by annual change percent (APC). The trend of APC was tested by t test (α=0.05). Results The incidence rate, ASIR, and rate of YLD of stroke in Chongqing in 2012 were 245.24/100,000, 201.47/100,000, and 3.37‰, respectively; while those in 2018 were 294.61/100,000, 222.43/100,000, and 4.03‰, respectively. The incidence rate and rate of YLD of stroke increased by 4.19% and 3.67% annually, respectively, and the changing trend showed statistically significant differences (t=2.66, P=0.045;t=2.61,P=0.048). The rate of YLD of stroke in males was higher than that in females. The mortality rate, ASMR and rate of YLL in Chongqing in 2012 were 96.29/100,000, 87.66/100,000, 18.38‰, respectively; while those in 2018 were 116.34/100,000, 95.88/100,000, 20.10‰, respectively, without statistically significant differences in the changing trend (all P>0.05). The rate of YLL of stroke was higher in males than in females as well as higher in rural area than in urban area. The rate of DALY of stroke in Chongqing in 2012 and 2018 was 21.75‰ and 24.13‰, respectively, with the APC of 1.51% and without statistically significant differences in the changing trend (t=1.33, P=0.240). The rate of DALY of stroke was higher in males than in femalesas well as higher in rural area than in urban area. The rate of DALY of stroke in urban area decreased by 5.82% annually, while the rate in rural area increased by 3.87% annually, showing a statistically significant difference in the changing trend (t=3.37, P=0.020; t=3.95, P=0.011). Conclusions Disease burden of stroke in Chongqing was lower than the national level, but higher than that ofdeveloped areas. Males and rural areaare the key to stroke prevention and control; and hence,it is necessary to implement tertiary measures for stroke prevention and control targeting males and rural area.
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2021, Vol. 28 
