Abstract：Objective To analyze the epidemiological characteristics and surveillance results of human infection with avian influenza A (H7N9) virus in Longhua New District of Shenzhen so as to provide a scientific basis for rational control and prevention of avian influenza (H7N9). Methods The information about the H7N9 cases reported and relevant surveillance in Longhua New District of Shenzhen during 2013-2015 was collected and descriptively analyzed. Results A total of 5 H7N9 cases were reported in Longhua New District of Shenzhen from 2013 to 2015, with 1 death. The median time from illness onset to laboratory confirmed diagnosis was 7 days, the median time from illness onset to pneumonia was 3.5 days and the median time from illness onset to antiviral treatment with Duffy was 4 days. All the patients had a history of exposure to live poultry markets before illness onset. We tested 626 samplesof the external environment oflive poultry markets in Longhua New District of Shenzhen from 2013 to 2015. 117 samples were positive to avian influenza virus H7 subtype, with the positive rate being 18.69%, and the positive rate of H7 subtype in the samplesof the external environment oflive poultry markets which related to patients’ exposure history reached up to 31.43%. However, the positive rate of H7 subtype in the samples of the external environment of poultry markets was significantly decreased after suspending live poultry trade (χ2=13.52, P<0.001). Conclusions The primary risk factor for human infection with avian influenza A(H7N9) appears to be exposure to live poultry markets and contaminated environment; and hence, banning live poultry trade can effectively decrease the opportunity of infection with avian influenza A(H7 subtype) from poultry markets.
何林, 周小锋, 许少坚, 王金明, 彭伟军. 深圳市龙华新区2013-2015年人感染H7N9禽流感发病及监测情况分析[J]. 实用预防医学, 2017, 24(6): 728-730.
HE Lin, ZHOU Xiao-feng, XU Shao-jian, WANG Jin-ming, PENG Wei-jun. Incidence and surveillance of human infection with avian influenza A(H7N9) virusin Longhua New District of Shenzhen, 2013-2015. , 2017, 24(6): 728-730.
[1] Gao R, Cao B, Hu Y, et al.Human infection with a novel avian-origin influenza A (H7N9) virus[J].N Engl J Med, 2013,368(20):1888-1897. [2] 秦彦珉,梅树江,谢旭,等. 深圳市25例人感染H7N9禽流感确诊病例流行病学分析[J]. 实用预防医学, 2015,22(8):952-955. [3] 吴家兵,侯赛,何军, 等. 安徽省人感染H7N9禽流感病例调查分析[J]. 中华疾病控制杂志,2015,19(8):778-781. [4] 陈兵,马智超,余光清. 深圳市宝安区4例人感染H7N9禽流感病例的流行病学分析[J]. 现代预防医学杂志, 2015,42(7):1176-1178. [5] Jefferson T, Jones M, Doshi P, et al. Oseltamivir for influenza in adults and children: systematic review of clinical study reports and summary of regulatory comments[J].BMJ, 2014, 348(15):1469. [6] 周蕾, 任瑞琦,张彦平, 等. 2014年9-12月中国内地人感染H7N9禽流感疫情流行病学特征分析[J]. 疾病监测, 2015,30(4):265-268. [7]Chen Y, Liang WF, Yang SG, etal. Human infections with the emerging avian influenza A H7N9 virus from wet market poultry:clinical analysis and characterisation of viral genome[J].Lancet, 2013,381(9881):1916-1925. [8]杨鹏,师鉴,马建新,等. 北京市首例人禽流感H5N1病例的感染来源调查[J].中华流行病学杂志,2009,30 (11):1114-1116. [9]胡锦峰, 王双英, 金涛, 等. 杭州市上城区8例人感染H7N9禽流感确诊病例流行病学分析[J].疾病监测, 2013, 28(9):717-719.
2017, Vol. 24 
