Abstract:Objective To investigate the transfer and pollution status of plasticizer in alcohol and evaluate its health risk by determining its concentration in marketed alcohol in Shenzhen so as to provide a scientific basis for alcohol safety. Methods Alcohol was sampled in ten districts of Shenzhen city in 2014-2016 based on the Food Safety Risk Monitoring Manual in Shenzhen. Plasticizer in alcohol was determined according to the detection methods listed in the National Food Pollutant Monitoring Manual. Results A total of 505 alcohol samples were collected for plasticizer determination in Shenzhen city from 2014 to 2016,and 23 samples exceeded the standard, with the over-standard rate of 4.55%. The over-standard ratedisplayed a decreasing tendency year by year (χ2tendency=4.273, P=0.039), and it was found to be the highest in 2014 (8.13%), but the lowest in 2015 (2.67%), with statistically significant differences in different years (χ2=6.949, P=0.031).The main excessive items were dibutyl phthalate (DBP) and di(2-ethylhexyl) phthalate (DEHP). The over-standard rates of plasticizer in different alcohol ranked from high to low as follows: 6.45% for other alcohol, 5.26% for liquor and 1.96% for red wine, without statistically significant differences(χ2=3.658, P=0.161). The over-standard rate of plasticizer was found to be the highest in Pingshan district (6.06%), but the lowest in Longhua district (2.63%), without statistically significant differences in different sampling sites(χ2=1.351,P=0.998). Health risk assessment indicated that DBP and DEHP intake via alcohol among residents in Shenzhen city was 0.14 g/(kg·bw) and 0.268 g/(kg·bw) respectively, which were far below the tolerable daily intake (TDI) of DBP [0.01 mg/(kg·bw) and DEHP (50 μg/(kg·bw)] set by the National Expert Committee for Food Safety Risk Assessment. Conclusions Different degrees of plasticizer transfer and pollution were found in marketed alcohol in Shenzhen city during 2014-2016, but they presented a decreasing tendency year by year. The main excessive items were DBP and DEHP, but their health risk for drinkers was within the acceptable levels.
李思果, 黄薇, 姜杰, 康莉, 潘柳波, 杨淋清, 罗贤如, 柯跃斌. 深圳市市售酒类塑化剂检测结果分析与风险评估[J]. 实用预防医学, 2019, 26(9): 1031-1033.
LI Si-guo, HUANG Wei, JIANG Jie, KANG Li, PAN Liu-bo, YANG Lin-qing, LUO Xian-ru, KE Yue-bin. Detection results and risk assessment of plasticizerin marketed alcohol in Shenzhen city. , 2019, 26(9): 1031-1033.
[1] 黄薇,彭朝琼,潘柳波.深圳市居民食物消费量与膳食营养状况的调查[M].广州:广东人民出版社,2015:32. [2] 王彝白纳,蒋定国,杨大进,等. 中国居民邻苯二甲酸二丁酯膳食摄入水平及其风险评估[J]. 中国食品卫生杂志,2016,28(6): 800-804. [3] 隋海霞,蒋定国,张磊,等. 中国居民成人饮酒者DEHP的风险评估[J].中国食品卫生杂志,2014,26(6):619-623. [4] Asakura H,Matsuto T. Experimental study of behavior of endocrine-disrupting chemicals in leachate treatment process and evaluation of removal efficiency[J]. Waste Manag,2009,29(6):1852-1859. [5] Genuis SJ,Beesoon S,Lobo RA,et al. Human elimination of phthalate compounds: blood,urine and sweat (BUS) study[J].Scientific World J,2012:615068. [6] Sampson J,de Korte D. DEHP-plasticised PVC: relevance to blood services[J]. Transfus Med,2011,21(2):73-83. [7] 王雪金,周云清,罗湘闽,等.邻苯二甲酸二丁酯对大鼠卵巢颗粒细胞中细胞凋亡因子Bcl-2、Bax表达的影响[J].实用预防医学,2015,22(2):155-158. [8] Singh S,Li SS.Bisphenol A and phthalates exhibit similar toxicogenomics and health effects[J]. Cene, 2012,494(1):85-91. [9] Quaak I, Brouns MR, Van de Bor M. The dynamics of autism spectrum disorders: how neurotoxic compounds and neurotransmitters interact[J].Int J Environ Res Public Health, 2013, 110(8):3384-3408. [10] 宋晓昀,张磊,姜杰. 2013年大连市部分市售食品污染物监测结果[J].职业与健康,2014,30(22):3225-3228,3231. [11] 王阳,赵婉婧,曹忠波,等. 辽宁省市售白酒中邻苯二甲酸酯类塑化剂的检测及结果分析[J].中国卫生检验杂志,2013, 23(15):3133-3134,3136.