Abstract：Objective To explore the results and changes of tuberculosis acid-fast bacilli sputum smear microscopy in Hanzhong City from 2012 to 2017, and to analyze the characteristics of smear-positive tuberculosis (TB) patients. Methods Data of sputum smear microscopy were collected from Chinese TB Management Information System and TB laboratory registration books. And sputum smear microscopy results in 2012-2017 were analyzed. Results During the 6-year period from 2012 to 2017, the smear-positive detection rates were declined from 6.48% to 4.42%. There were statistically significant differences in the incidence rates in different years (P<0.05), in the sputum smear-positive rates in different counties/districts (P<0.05), in the detection rates of smear-positive TB patients among different age groups (P<0.01) and in the male-to-female ratio among smear-positive TB patients (P<0.01). The age group of 45-54 years had the maximum number of smear-positive TB patients, accounting for 19.60%, followed by the age group of 55-64 years, accounting for 17.04%. Male TB patients were more than female ones, with the male-to-female patient ratio of 2.82:1. Conclusions The TB epidemics in Hanzhong City in 2012-2017 presented a downward trend. Males, the middle-aged and the elderly were the key populations for TB prevention and control.
[1] 郭永博,王静,张琳,等.改良抗酸染色在结核性浆膜炎临床诊断中的价值及应用[J].第四军医大学学报,2015,44(8):64-66. [2] Steingart KR, Henry M, Ng V,et al.Fluorescence versus conventional sputum smear microscopy for tuberculosis:a systematic review[J]. Lancet Infect Dis,2006,6(9):570-581. [3] Cuevas LE, Al-Sonboli N, Lawson L,et al.LED fluorescence microscopy for the diagnosis of pulmonary tuberculosis:a multi-country cross-sectional evaluation[J]. PLoS Med,2011,8(7):e1001057. [4] Chaidir L, Parwati I, Annisa J,et al.Implementation of LED fluorescence microscopy for diagnosis of pulmonary and HIV-associated tuberculosis in a hospital setting in Indonesia[J].PLoS One,2013,8(4):e61727. [5] Khatun Z, Kamal M, Roy CK,et al.Usefulhess of light-emitting diode(LED) fluorescent microscopy as a tool for rapid and effective method for the diagnosis of puhnonary tuberculosis[J].Bangladesh Med Res Counc Bull,2011,37(1):7-10. [6] 赵雁林,姜广路.中国结核病防治规划痰涂片镜检标准化操作质量保证手册[M].北京:中国协和医科大学出版社,2009:7-14. [7] 陈明亭,万康林.结核病实验室技术手册[M].北京:科学出版社,2011:34-44. [8] 李源,高风华. 淄博市2008－2013年肺结核痰涂片镜检结果分析[J].中国卫生检验杂志,2015,25(10):1649-1651. [9] 夏辉,赵冰,李强,等.发光二极管荧光显微镜在基层应用的多中心研究[J].中国防痨杂志,2011,33(9):592-595. [10] 姜广路,马异峰,李云絮,等.发光二极管荧光适配器显微镜的实验室诊断效果评价[J]. 中国防痨杂志,2012,34(2):127-128. [11] 宋媛媛,蒋明霞,郭占清,等.发光二极管荧光显微镜检测结核分枝杆菌在基层实验室的应用评价[J].中国防痨杂志,2014,36(7):515-519. [12] 蒋卫平.结核分枝杆菌金胺O荧光和萋-尼染色显微镜镜检结果比较[J].医学信息,2016,29(22):278-279. [13] 喻红玲.荆门市城区新生儿卡介苗免疫效果评价[J].公共卫生与预防医学,2012,23(1):81-82. [14] 丁守华,万青灵,邵文荣,等. 江苏淮安市2011－2015年肺结核流行病学分析[J].中国热带医学,2017,17(8):791-794. [15] 汪德华,付军,刘玲燕,等.2010－2015年南昌市肺结核病流行特征分析[J].实用预防医学, 2018,25(1):7-10. [16] 马树波,王娜,杨震,等.2006－2015年北京市昌平区肺结核报告发病情况分析[J].实用预防医学,2016,23(10):1176-1181.
2019, Vol. 26 
