Abstract:Objective To analyze the epidemiological characteristics of infectious diarrhea other than cholera, dysentery, typhoid and paratyphoid in Hunan Province from 2005 to 2016, and to provide a scientific basis for their prevention and control. Methods Statistical statements and information of the reported other infectious diarrhea cases in Hunan Province during 2005-2016 were collected from Infectious Disease Report Information System of the National Disease Prevention and Control Information System, and then descriptive epidemiological analysis was performed. Results A total of 262,396 other infectious diarrhea cases were reported in Hunan Province from 2005 to 2016. The annual reporting incidence rates were between 15.84/100,000 and 45.57/100,000, with a rising trend (χ2tendency=16,974.39, P<0.001). Most of the cases were aged under 5 years old(55.0%)and 60 years and above(10.8%). The majority of the patients were scattered children(52.1%) and farmers (22.2%). There were two incidence peaks in summer (from July to September) and winter (from November to January of the following year) in each year. The top five cities with high annual incidence rate were Yongzhou City (71.6/100,000), Zhuzhou City (63.8/100,000), Loudi City (56.5/100,000), Changsha City (50.8/100,000) and Zhangjiajie City (38.9/100,000). Cases with viral or bacterial infection accounted for 90.3% (3,318/3,676) and 9.06% (333/3,676) respectively. Cases with rotavirus infection accounted for 93.1% of the viral infection cases, while cases with Salmonella infection occupied 67.3% of the bacterial infection cases. The peak of bacterial infection occurred in May-October, while the peaks of viral infection in January and November-December. Conclusions There were two incidence peaks of other infectious diarrhea occurring in summer and winter in Hunan Province during 2005-2016. Scattered children under 5 years old, the elderly aged 60 years and above and farmers were the high risk groups. The main pathogens causing infections were rotavirus and Salmonella. Most of the cases occurred in summer and autumn were caused by bacterial infection, while most of the cases occurred in winter and spring by viral infection.