摘要目的 分析2013年南通市经济技术开发区(开发区)恶性肿瘤的死亡流行特征及疾病负担,为恶性肿瘤防治提供科学依据。 方法 通过计算恶性肿瘤死亡率、标化死亡率、伤残调整寿命年(disability adjusted life years,DALYs)、早死所致寿命年(years of life lost,YLLs)和残疾所致寿命年(years lived with disability,YLDs)指标,分析主要恶性肿瘤的疾病负担和人群分布特征。 结果 2013年南通市开发区恶性肿瘤死亡率为209.88/10万,标化死亡率为103.20/10万。恶性肿瘤所致DALYs率为20.66/千人,男性和女性分别为26.97/千人和14.50/千人。恶性肿瘤DALYs损失以YLLs为主,占86.27%。DALYs前5位与死亡率顺位一致,依次为肺癌、肝癌、胃癌、结直肠癌和食管癌,其中男性DALYs率最高的为肝癌6.66/千人,女性DALYs率最高的是肺癌3.13/千人。 结论 肺癌和肝癌仍是危害南通市开发区居民健康的主要癌种,45岁以上人群是预防和干预的重点人群,应针对性开展筛查和防治工作,以减少疾病负担。
Abstract：Objective To analyze the epidemiological features of death cases and disease burden of malignant tumors among residents in the Economic and Technological Development Area of Nantong City in 2013, and to provide a scientific basis for prevention and control of malignant tumors. Methods The disease burden and population distribution features of the main malignant tumors were determined by analyzing the mortality, standardized mortality, disability adjusted life years (DALYs), years of life lost (YLLs) and years lived with disability (YLDs) induced by malignant tumors. Results The crude mortality and age-standardized mortality of malignant tumors in the Economic and Technological Development Area of Nantong City in 2013 were 209.88/100,000 and 103.20/100,000 respectively. The DALYs of malignant tumors was 20.66 years per 1,000 persons (26.97 for male and 14.50 for female). The DALYs loss was mainly due to YLLs, accounting for 86.27%. Lung cancer, liver cancer, stomach cancer, colorectal cancer and esophageal cancer were the top five cancers of both mortality and DALYs. The DALYs of liver cancer ranked the first in male (6.66 years per 1,000 persons), while that of lung cancer ranked the first in female (3.13 years per 1,000 persons). Conclusions Lung and liver malignancies are the main cancers affecting the health of residents in the Economic and Technological Development Area of Nantong City, and the residents aged 45 years and above are the key population in prevention and control of malignancies. It is necessary to conduct the targeted screening and perform prevention and treatment so as to reduce the burden of disease.
潘少聪, 张之海, 戴垚垚, 陈杰. 南通市经济技术开发区居民2013年恶性肿瘤疾病负担分析[J]. 实用预防医学, 2018, 25(9): 1060-1063.
PAN Shao-cong, ZHANG Zhi-hai, DAI Yao-yao, CHEN Jie. Disease burden of malignant tumors among residents in the Economic and Technological Development Area of Nantong City, 2013. , 2018, 25(9): 1060-1063.
2018, Vol. 25 
