Association between frequency of fresh fruit intake and stroke incidence among residents in Liuyang City
YIN Li1, LIU Hui-lin1, YIN Lei1, PEI Pei2, CHEN Jian-wei3, DU Huai-dong4
1. Hunan Provincial Center for Disease Control and Prevention, Changsha, Hunan 410005, China; 2. Chinese Academy of Medical Sciences, Bejing 100730, China; 3. Liuyang Municipal Center for Disease Control and Prevention, Changsha, Hunan 410300, China; 4. Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, Oxford OX 7LF, UK
Abstract：Objective To understand the frequency of fresh fruit consumption among residents in Liuyang City, and to explore the correlation between the frequency of fresh fruit consumption and the incidence of stroke. Methods We collected the data regarding permanent residents aged 30-79 years from the baseline survey of China Kadoorie Biobank (CKB) in the project site, Liuyang City of Hunan Province and the follow-up data about stroke incidence. Cox proportional hazards regression analysis was conducted to estimate the association between the frequency of fresh fruit consumption and the risk of stroke after adjusting for confounding factors. Results A total of 57,288 participants were recruited in the baseline survey, and only 7.38% of the participants consumed fresh fruits ≥ 4 days per week. Participants with lower frequency of fresh fruit consumption tended to be males, have low annual family income and a low level of education, and be current smokers and current drinkers (P<0.001). A total of 2,720 incident stroke cases were recorded during the follow-up from 2015 to 2019. Fresh fruit consumption had an inverse association with stroke incidence. Compared with the participants who never consumed fresh fruit, respondents who consumed fresh fruit ≥ 4 days per week had a 28% lower risk of stroke incidence (HR=0.72, 95%CI: 0.61-0.85), and the corresponding risk reduction was 25% (HR=0.75, 95%CI: 0.60-0.94) for ischemic stroke and 51% (HR=0.49, 95%CI: 0.35-0.76) for hemorrhagic stroke. Conclusion Increasing the frequency of fresh fruit consumption may have a beneficial effect on prevention of stroke. The consumption of fresh fruits among the residents in Liuyang City is not optimistic; and hence, appropriate measures need to be taken to increase the consumption level.
殷黎, 刘慧琳, 殷蕾, 裴培, 陈建伟, 杜怀东. 浏阳市居民新鲜水果摄入频率与脑卒中发病的关联[J]. 实用预防医学, 2022, 29(4): 443-446.
YIN Li, LIU Hui-lin, YIN Lei, PEI Pei, CHEN Jian-wei, DU Huai-dong. Association between frequency of fresh fruit intake and stroke incidence among residents in Liuyang City. , 2022, 29(4): 443-446.
[1] 王陇德,常继乐,张宗久.中国脑卒中防治报告2019[M].北京:人民卫生出版社,2020. [2] 中国脑卒中防治报告编写组. 《中国脑卒中防治报告2019》概要[J]. 中国脑血管病杂志,2020,17(5):272-281. [3] Dauchet L,Amouyel P,Dallongeville J. Fruit and vegetable consumption and risk of stroke: a meta-analysis of cohort studies[J]. Neurology,2005,65(8):1193-1197. [4] Oude GL, Verschuren WM, Kromhout D, et al. Raw and processed fruit and vegetable consumption and 10-year stroke incidence in a population-based cohort study in the Netherlands[J]. Eur J Clin Nutr,2011,65(7):791-799. [5] Sauvaget C, Nagano J, Allen N, et al. Vegetable and fruit intake and stroke mortality in the Hiroshima/Nagasaki Life Span Study[J]. Stroke,2003,34(10):2355-2360. [6] Du H, Li L, Bennett D, et al. Fresh fruit consumption and major cardiovascular disease in China[J]. N Engl J Med,2016,374(14):1332-1343. [7] 李立明,吕筠,郭彧,等. 中国慢性病前瞻性研究:研究方法和调查对象的基线特征[J]. 中华流行病学杂志,2012,33(3):249-255. [8] Chen Z, Lee L, Chen J, et al. Cohort profile: the Kadoorie Study of Chronic Disease in China (KSCDC)[J]. Int J Epidemiol,2005,34(6):1243-1249. [9] 赵文华,丛琳. 体力活动划分:不同类型体力活动的代谢当量及体力活动的分级[J]. 卫生研究,2004,33(2):246-249. [10] 孙海欣,王文志. 中国脑卒中患病率、发病率和死亡率调查结果发表[J]. 中华神经科杂志,2017,50(5):337. [11] Du H, Li L, Bennett D, et al. Fresh fruit consumption and all-cause and cause-specific mortality: findings from the China Kadoorie Biobank[J]. Int J Epidemiol,2017,46(5):1444-1455. [12] Zhang X,Shu X,Xiang Y,et al. Cruciferous vegetable consumption is associated with a reduced risk of total and cardiovascular disease mortality[J]. Am J Clin Nutrit,2011,94(1):240-246. [13] 丁贤彬,陈婷,白雅敏,等.健康管理对重庆市机关事业单位慢性病高风险人群生活方式的影响[J].实用预防医学,2020,27(3):257-261,281. [14] Aune D,Giovannucci E,Boffetta P,et al. Fruit and vegetable intake and the risk of cardiovascular disease, total cancer and all-cause mortality—a systematic review and dose-response meta-analysis of prospective studies[J]. InternatJ Epidemiol,2017,46(3):1029-1056. [15] Threapleton DE,Greenwood DC,Evans CE,et al. Dietary fiber intake and risk of first stroke: a systematic review and meta-analysis[J]. Stroke,2013,44(5):1360-1368. [16] 田小草,汪韶洁,李善鹏,等. 青岛市成年人水果摄入与脑卒中发病关联的前瞻性研究[J]. 中华流行病学杂志,2019,40(5):515-520.
2022, Vol. 29 
