Abstract:Objective To investigate the epidemic characteristics and trend of sexually transmitted diseases (STD) in Zhuhai city so as to provide a reference basis for developing STD prevention and control strategies. Methods An epidemiological statisticalanalysis was performed on the data regardingmonitored cases about five types of STDs, including gonorrhea, syphilis, genital warts, genital herpes and Chlamydia trachomatis infection, in Zhuhai city between 2014 and 2018. Results The reported incidence rate of the STDs increased from 276.70/100,000 in 2014 to 331.54/100,000 in 2018, with an annual average increase of 4.62%, of which the incidence of gonorrhea and genital Chlamydia trachomatis infection increased significantly, while the incidence of syphilis went up first and then went down. The incidence rate in urban streets was 455.49/100,000, with the highest incidence rate in Gongbei subdistrict. The incidence rate in rural areas of the suburbs was 180.00/100,000, with the highest incidence rate in Jing’an town. A statistically significant difference was observed between the urban and suburb areas. The reported incidence rates of STDs in the males and females showed an overall upward trend, and the male to female gender ratio was 1.61∶1, of which the gender ratios in gonorrhea and genital Chlamydia trachomatis infection were 12.60∶1 and 0.51∶1, respectively. Most of the STD cases were found in the age group of 20-39 years (503.23/100,000), and the incidence rate in the age group of 50-59 years increased most rapidly, with the annual average increase of 9.08%. The incidence rate of syphilis was higher in the age group above 50 years than in the other age groups as well as the other STDs groups aged above 50 years. The most common occupations were housekeeping and unemployment (28.98%). Conclusions The epidemic situation of the STDs in Zhuhai city during 2014-2018 presented an overall rising tendency, with obvious regional clustering in urban streets. Corresponding prevention and control measures should be adopted according to the epidemic features of the STDs in Zhuhai city.