Abstract：Objective To investigate the concentration and distribution characteristics of 9 categories (32 species) of antibiotics, including macrolides, β-lactams, quinolones, lincosamides, sulfonamides, tetracyclines, antifungals, nitromidazoles and chloramphenicols, in Dongguan urban section of the Dongjiang River. Methods A high performance liquid chromatography-tandem mass spectrometry method using solid phase extraction was employed to determine antibiotics in water samples, and the pollution characteristics of antibiotics in Dongguan urban section were analyzed according to the results. Results During the sampling period, 7 categories (10 species) of antibiotics, including macrolides, β-lactams, quinolones, lincosamides, sulfonamides, antifungals and nitromidazoles were detected in 3 sampling sites, of which the detection rates of lincomycin and fluconazole were both 100%, and the highest concentration of azithromycin was 265.1 ng/L. Conclusions Water in Dongguan urban section of the Dongjiang River has been polluted by antibiotics, and the total concentration of antibiotics is at a moderate to inferior level. It is necessary to strengthen the regular monitoring of antibiotics in Dongguan urban section of the Dongjiang River and take corresponding measures so as to reduce the residual pollution level of antibiotics in water.
2020, Vol. 27 
